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10.1038/35098027 33 Snchez-CrdenasC.MontoyaF.NavarreteF

When these mice where administered IGF-1 they showed lowered fasting glucose, and because no functional IGF-1R is present in muscle, such effect is believed to be due to renal gluconeogenesis suppression [129, 163]

Expi293F (A14527, Thermo Fisher Scientific) cells were cultured in SMM 293-TII-N medium (Sino Biological Inc.) with 1% p/s at 37 C in a 5% CO 2 atmosphere