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Joint injections commonly deliver medications like corticosteroids or hyaluronic acid directly into the affected joint, providing targeted relief and reducing inflammation

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In particular, we previously showed that CD38 is the main NAD + -hydrolyzing enzyme in mammalian tissues, and its upregulation largely accounts for age-dependent decline in NAD + 11,17,18,19

With the angle of injection being anything significant, it is impossible to hit the sciatic nerve