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Therefore, GSH, and the GSH/GSSG balance, play a crucial role in cell survival and cytotoxicity, and should be considered for the design of antitumor therapy and the reversion of drug resistance [72, 75]

In rat thoracie aorta

Mitochondrial dysfunction in perimenopausal mood disorders is often accompanied by oxidative stress and neuronal injury

1 This process is less complicated by oxidative damage, allowing a more direct path to tissue recovery

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Beyond its previously reported modulation of autophagy via the Phosphatidylinositol 3-Kinase (PI3K)/AKT Serine/Threonine Kinase (AKT)/Mechanistic Target of Rapamycin (mTOR) pathway and NF-B inhibition 61,62 , our findings revealed that palmatine s mechanism involves a novel target network