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These benefits were accompanied by a significant reduction in the blood levels of homocysteine, a molecule with neurotoxic effects that is elevated in ALS patients and whose conversion into another molecule is dependent on methylcobalamin

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Neurological complications are seen in 75 to 90 percent of deficiency cases, whether anemia is also observed or not

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Although NR has shown promising results in this context, further studies are necessary to establish the efficacy and safety of NR in HF patients