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Conflict of Interest The author declares that this research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest

References: [1]Current Patent Assignee: PROTEOSTASIS THERAPEUTICS - WO2015/196071, 2015, A1 Location in patent: Paragraph 0274

Autophagy mediates 2-methoxyestradiol-inhibited scleroderma collagen synthesis and endothelial-to-mesenchymal transition induced by hypoxia

What the Research Shows So Far BPC-157 has been studied for over two decades in animal models and preclinical studies, with consistent findings across a wide range of tissues and systems: BPC-157 has shown an extremely high safety margin in rodents, with no toxicity or organ damage reported even at doses much higher than those typically used in humans. Sikiric, P

[1] [2] Testosterone, by contrast, is a well-established androgen hormone used therapeutically in the UK for conditions such as confirmed hypogonadism and, under specialist supervision, as part of gender-affirming hormone therapy (which is generally considered off-label use in the UK and requires specialist oversight)

An overview of extracellular matrix-based bioinks for 3D bioprinting