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13a, Supplementary Table 9), suggesting that the distinct rotamer orientation of H296 ECL2 in Cagri-bound CTR (to accommodate the Glu linker) and/or the observed more open ECL3 conformation induced by the lipidated peptide may facilitate or stabilize an active CTR conformation (Supplementary Fig

Two distinct melanin pigments are produced by melanocytes in the epidermis: pheomelanin, a yellow-red pigment

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Its stability in gastric juice for at least 24 hours makes this a viable route, particularly effective for promoting healing in gastrointestinal tissues

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