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Abstract Cells contain a large number of antioxidants to prevent or repair the damage caused by reactive oxygen species, as well as to regulate redox-sensitive signaling pathways

Glutathione, a water-soluble tripeptide composed of -l-glutamyl-l-cysteinylglycine, exists in reduced (GSH) and oxidized (GSSG) forms

Upon exposure of prostate stromal cells to hypoxic conditions, ERS is activated in a time-dependent manner, leading to the secretion of various growth factors and pro-inflammatory cytokines (TGF-1, FGF-2, and IL-8), which subsequently induce BPH [78]

MiR-1-3p enhances the sensitivity of ovarian cancer cells to ferroptosis by targeting FZD7

To be effective, Glutathione injections need to be done on a regular basis

Biochimica Biophysica Acta - General Subj