can l-carnitine cause ventricular hypertrophy

can l-carnitine cause ventricular hypertrophy and heart disease Carnitine Deficiency: What Is It,

Name: can l-carnitine cause ventricular hypertrophy and heart disease Carnitine Deficiency: What Is It,
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Carnitine Deficiency: What Is It, Causes, Symptoms, and More Osmosis Primary carnitine deficiency cardiomyopathy International Journal of Cardiology Cardiac function and incidence of unexplained myocardial scarring in patients with primary carnitine deficiency a cardiac magnetic resonance study Scientific Reports Comprehensive review of the expanding roles of the carnitine pool in metabolic physiology: beyond fatty acid oxidation PMC Carnitine is a friend in HFpEF and foe in HFrEF ScienceDirect The effects of L carnitine supplementation on lipid profiles in adults: A systematic review and dose response meta analysis ScienceDirect

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This alteration suppressed GATA3 expression via the bile acid-Takeda G protein-coupled receptor 5(TGR5)-cyclic adenosine monophosphate (cAMP) signaling pathway, leading to a marked ~90% reduction in IL-22 secretion from intestinal group 3 innate lymphoid cells (ILC3s), which subsequently induced insulin resistance, ovarian dysfunction (characterized by increased follicular cysts and decreased corpora lutea), and impaired fertility (82)