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Nonlinear mixed-effects modeling also supports maturity-adjusted dosing to optimize exposure and reduce variability (Table 3) (144, 147)

doi: 10.3390/ijms21197098 3 WangHYangJZhangKLiuJLiYSuWet al

Hepatology 58 , 15871597 (2013)

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31, 32 The second issue is that, although World Health Organization proposed lower BMI cutoff points for obesity among Asians, 33 cohort studies about the relationships between BMI and mortality do not seem to consistently support the need for lower BMI thresholds for the Asian population

81 These TM requirements are not a one-size-fits-all parameter, as they vary considerably and are affected by factors such as breed, physiological status (e.g