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Goal: Support pulsatile GH release through synergistic GHRH + GHS stimulation [4]

Adolescents with type 1 diabetes experiencing nocturnal hyperglycaemia had higher sleep onset latency, increased light sleep percentage and higher arousal index compared with control individuals, indicating that hyperglycaemia leads to fragmented and less restorative sleep [37]

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It is used in cell culture assays (fibroblast proliferation, collagen synthesis), rodent wound models, and gene expression studies investigating age-related transcriptomic changes