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Here is a clear-eyed overview of where the evidence stands across the three peptides most relevant to PMOS

Springer Nature Switzerland, Cham, pp 345357 Guo D, Liu Z, Zhou J et al (2024) Significance of programmed cell death pathways in neurodegenerative diseases

A healthy gut microbiome also mediates how available and how toxic ingested metals are, and probiotics can buffer metal-induced dysbiosis

Although this viewpoint is plausible, the precise molecular mechanisms still require further exploration to better elucidate the regulation of apoptosis by mitophagy