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A deficiency in vitamin B12 in pregnancy can lead to serious complications, including developmental delays, neural tube defects, and maternal fatigue or anaemia

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Deletion of the GSTM1 gene can lead to inactivation of GST-, altering a resistance to poisons and carcinogens, what can result in the loss of detoxification capacity and increasing the risk of cancer development [23]

Unfortunately, it is not routine to assess manganese levels in patients presumed to have PD, and little research has been done on chronic, low-level exposure to ambient manganese (i.e., from industrial waste.) As imaging techniques improve and become more readily available, it will be easier to differentiate manganism from PD

[DOI] [PubMed] [Google Scholar] Min Z.H., Wang L.Y., Jin J.J., Wang X.D., Zhu B.J., Chen H., et al

Mainly such products consist of hydroquinone, mercury, and steroids which cause destruction in sensitive regions as most of these chemicals can have very hazardous effects in any case