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In addition to this, there was also a small but significant increase in an unidentified processing fragment at ~64 kDa, as well as a significant decrease in a peptide at ~100 kDa, which is likely to be the sAPP fragment (Appendix Fig

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Symptoms can overlap with thyroid dysfunction: Cold intolerance Hair thinning Fatigue Slowed metabolism Iron infusions support endocrine function by replenishing iron required for proper thyroid hormone production

Metabolic flux Substrate use in a biochemical pathway determined as the turnover rate of a metabolite as opposed to its steady-state levels, which can be constant in different conditions despite widely varying flux rates