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In addition, factors such as lipotoxicity, defects in the incretin system, hyperglucagonemia, increased renal glucose reabsorption, and central insulin resistance contribute to the progression of diabetes

In the bile ducts bacterial glucuronidases will produce unconjugated bilirubin from bilirubin glucuronide with formation of insoluble calcium bilirubinate stones when the unconjugated bilirubin complexes with calcium

Although great efforts have been made in studying the different kinds of CPT agonists/antagonists, only a few pharmaceuticals have been applied for clinical uses

Lee TH, Yau S (2020) From obesity to hippocampal neurodegeneration: pathogenesis and non-pharmacological interventions

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The restoration of neuronal mitophagy was indicated to enhance the phagocytic efficiency of microglia [15]