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[Google Scholar] Serum Vitamin C concentration is low in peripheral arterial disease and is associated with inflammation and severity of atherosclerosis

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It also plays a critical role in maintaining cellular health by directly neutralizing free radicals, as well as by maintaining the activity of vitamins C and E

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Ideally, this framework is further enriched with metagenomic analysis of the gut microbiome, which provides valuable insights for functional decision-making (Proctor et al., 2019), and with a pharmacogenomic profile, particularly in cases requiring pharmacotherapy or where patients are already on complex polypharmacy regimens