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It demonstrates potent anti-glioblastoma activity by: (1) blocking tumor invasion and cytokinesis (inducing polyploidy), (2) disrupting mitochondrial dynamics to elevate ROS and trigger ferroptosis, and (3) sensitizing tumors to radiotherapy/kinase inhibitors via ROS-driven PDGFR/mTOR pathway activation

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Ten nanomolar cells show up repeatedly as a working dose for collagen and growth experiments

Cu chelators A number of Cu-chelating agents such as TTM, trientine, and d-penicillamine have been developed and tested for their anti-tumor activity in both animal models as well as in clinical trials

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