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Description

In CD4, the additional strand G is formed by residues 166172 (PDB: 4h8w)

TPM203 was well tolerated in a phase I trial evaluating 17 patients with PV in whom increased Tregs and reduced Th17/Th17.1 and Dsg3-specific T cells as well as decreased anti-Dsg3 IgG levels were observed following TPM203 treatment [59, 60]