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228 This adaptability makes CSCs highly resistant to metabolic inhibitors, as they can reprogram their energy sources when one pathway is blocked

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In addition, the amino groups of arginine and lysine bind with carbonyl groups of carbohydrate can also produce advanced glycation end products, such as glucosepane, pentosidine, and hydroimidazolone [22]

We also review the recent progress in attenuating the molecular mechanisms of the NF-kB Pathway by phytochemicals, which may open up novel therapeutic avenues

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