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Description

Generally well-tolerated in human trials at research doses with no major safety concerns reported [19]

Plasmids pET28a, pCDFDuet-1, and pACYCDuet-1 were used for plasmid construction and protein expression

Diabetes Metab Syndr Obes Targets Ther

Klin Monbl Augenheilkd

Through membrane proteomics screening using biotin-labeled PROTAC probes, the team identified CD36 as a major binding partner of both CRBN- and VHL-based PROTACs, as well as several non-traditional small-molecule therapeutics such as rapamycin and doxorubicin