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Discovery of novel benzylaniline derivatives containing chloroacetamide as GPX4 inhibitors with potential efficacy in triple negative breast cancer ScienceDirect Identification, optimization, and structural elucidation of chloroacetamide scaffold as covalent inhibitors for Ubiquitin C terminal Hydrolase L3 bioRxiv Expanding the Chemistry of Dihaloacetamides as Tunable Electrophiles for Reversible Covalent Targeting of Cysteines Journal of Medicinal Chemistry Targeting a Therapy Resistant Cancer Cell State Using Masked Electrophiles as GPX4 Inhibitors bioRxiv Glutathione dynamics in subcellular compartments and implications for drug development ScienceDirect Heat Shock Protein 90 Interactome Mediated Proteolysis Targeting Chimera (HIM PROTAC) Degrading Glutathione Peroxidase 4 to Trigger Ferroptosis Journal of Medicinal Chemistry

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