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Biomaterials 30, 27992806

doi: 10.1073/pnas.0914984107

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T1-P19 The prevalence of Plasmodium vivax and G6PD deficiency in the Mandoto district in Madagascar and the Shashemene district in Ethiopia, results of a large observational study in preparation of the PvSTATEM cluster-randomized study van der Pluijm RW 1 , Emiru T 2 , Randrianarisoa MM 3 , Irinantenaina J 3 , Mangahasimbola R 3 , Kassa FA 2 , Chali W 2 , Randrianarivelojosia M 3 , Fanjasoa R 3 , Obadia T 1 , Pelleau S 1 , Byrne I 4 , Harimanana A 2 , Bradley J 4 , Gadisa E 2 , Haile K 2 , Witkowski B 3 , Randremanana R 3 , Tadesse F 2 , Drakeley C 4 , White M 1 1 Institut Pasteur, Paris, France

For UA conjugated metabolites, glucuronidation enhances the molecules hydrophilicity, promoting renal excretion, whereas sulfation may attenuate the biological activity of the UA monomer