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The anti-tumor effect of the combination of PTDSS1 inhibitor and RSL3 was examined in vivo experiments A subcutaneous xenograft tumor model was established in nude mice using Kyse30 cells with high expression of PTDSS1

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In the autograft group, although the arrangement of sciatic nerve fibers in proximal parts was disrupted, this nerve was intact in the middle and distal parts (Fig

The results revealed that, except for the metabolic organs liver and kidney, the tumor tissue exhibited the highest fluorescence intensity, further confirming the excellent tumor targeting of NP4 (Fig