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5, MSG meaningfully upregulated HMGB1 (Fig

Studies indicate that in typical microenvironments, BMSCs undergo osteogenic differentiation and complete the bone regeneration process, effectively repairing bone injuries

367 In human PASMCs exposed to hypoxia or treated with PDGF, phosphorylation of ERK/Akt increases, contributing to the upregulation of HIF-1, 368 which activates p38/15-LO pathway to upregulate NDUFA4L2, thereby promoting lipid oxidation and ROS, leading to increased cell proliferation

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Bacterial suspensions were then diluted 1:100 in BHI + 10% FCS media and 50 l were added to a sterile 96-well microtiter plate containing twofold serial dilutions of the compound in media (50 l) in technical triplicates

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