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Severe reactions are rare, and any discomfort usually dissipates after a few minutes

If it occurs, HIV-associated oral mucosal melanin hyperpigmentation usually develops within 2 years of contracting HIV or within a few months of starting antiretroviral treatment with the drug zidovudine

It is currently FDA-approved for treating hypoactive sexual desire disorder (HSDD) in premenopausal women in selected countries

Seborrheic keratoses present as sharply marginated, square-shouldered, tan, brown, or black papules 10 to 15 mm wide and 2 to 10 mm tall (Figs

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