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Depictions of the groucho-binding motif and the runt domain (RD) are given

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Given the comorbidities of ASD with OCD and Tic disorder (e.g., (96)), and similarities of OCD and Tic-related behaviors to some autism-related RRBs, these findings suggest the possibility that RRBs among individuals with the later-onset subtype of ASD may, like some other ASD-related traits, differ in their manifestations and causes from individuals with early-onset ASD

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There is a crucial need for therapies that can lead to improved outcome after neonatal and pediatric brain injury as the currently used therapies are only partially effective [134, 135, 169172]

[PubMed: 12388174] 484