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doi: 10.1016/j.ecoenv.2025.118691

However, most of the investigation was performed at the preclinical level, thus, it is essential to carry out the human trial to translate the findings into clinical use

Darke, A

Combining a USP8 inhibitor with a ferroptosis inducer enhances the clonal expansion of CD8 + T cells and impedes colorectal tumor growth, thereby enhancing the antitumor response to PD-1 immunotherapy in vivo [285]