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Pangamic acid ('vitamin B15)

AC and JS wrote the first draft of the manuscript

Nutrients 14(7): 1494

Several recent studies have pointed out that alterations of the gut microbial tryptophan metabolism influence peripheral Trp availability, affecting central tryptophan levels and, thereby, leading to changes in the central serotonin metabolism (171, 172)

NCT03921879, Table 1) Other NAMPT inhibitors, including LSN3154567, STF-31, STF-118804, GNE-617, and CB 300919, have not entered clinical trials due to their high toxicity or low safety