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Contemporary scientific investigations have validated the fact that traditional botanical drugs and their formulations derived from TCM and TM possess distinctive benefits for preventing and treating HACE by modulating mechanisms such as anti-hypoxia, hypoxic pulmonary hypertension reduction, angiogenesis and vasoconstriction inhibition, decreased blood-flow resistance, reduced cell permeability, inflammatory response alleviation, and anti-oxidative stress (Xie et al., 2022)

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Nagy P, Beal JL, Ashby MT (2006) Thiocyanate is an efficient endogenous scavenger of the phagocytic killing agent hypobromous acid

In the REDEFINE 1 phase 3 trial, cagrilintide 2.4 mg monotherapy produced an average body weight reduction of 11.8% over 68 weeks

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Of the 49 patients with clinical evidence of CSPH, only 40.8% (95% CI 27.8%55.3%) met the Rule of Five criteria for ruling in CSPH