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In terms of anti-inflammatory actions, it reduces the expression of pro-inflammatory mediators such as monocyte chemotactic protein-1 (MCP-1), interleukin-1 (IL-1), tumor necrosis factor-alpha (TNF-), interleukin-6 (IL-6), and cyclooxygenase-2 (COX2), which are significantly elevated in type 2 diabetes (Pivari et al., 2019)

doi: 10.3390/plants10020293 211 WarburtonM

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Losartan for the treatment of hypertension and left ventricular hypertrophy: the Losartan intervention for endpoint reduction in hypertension (LIFE) study