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Due to their high rate constant and high abundance, Prx are thought to be responsible for scavenging nanomolar concentrations of H 2 O 2 associated with redox signaling, while Gpx are likely important at higher intracellular concentrations, buffering high ROS levels to avoid cell damage and stress signaling response (Sena and Chandel, 2012)

Diabetes Care 31, 940944

Makrilakis K

Studies focus on its ability to amplify natural growth hormone pulses through pituitary stimulation

Reciprocally, an increased autophagic flux and the recycling of cellular macromolecules upon extended inhibition of mTORC1 is sufficient to partially replenish intracellular or intra-lysosomal amino acid pools and to partially reactivate mTORC1 (Yu et al., 2010