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doi:10.1016/j.bbalip.2014.09.002

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Subsequently, differentially expressed gene (DEG) analysis was performed on SA-AKI samples and control samples

Therefore, it is possible that GPX1, as an essential antioxidant enzyme, attenuates AIF release and enhances the expression of Bcl-2 to inhibit cell apoptosis, by reducing ROS level

Caspase-8 is triggered by death receptors in the extrinsic pathway, while Caspase-9 is activated as a result of mitochondrial damage in the intrinsic pathway