The neuroprotective role of estrogens implies a close regulation of processes such as (i) anti-oxidant activity (Kumar et al., 2010), (ii) DNA repair (Bethea et al., 2016), (iii) synthesis of growth factors (Scharfman and MacLusky, 2006), (iv) synaptic plasticity (McEwen and Milner, 2007), and (v) the blood flow to the brain (Chambliss et al., 2000)
More commonly, however, NO was associated with inhibition rather than activation of antioxidant enzymes
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Haematologica 91 (7), 873880

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Urinary dopamine and serotonin were assayed utilizing commercially produced RIA kits (3-CAT RIA IB88501 and IB89527