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An increase in the epidermal layer was also detected at the end of the experiment

Emerging preclinical and clinical studies have shown that the combination of ICB with immunogenic drugs, such as chemotherapeutic agents that induce ICD, could enhance ICB efficacy by evoking the activation of antecedent T lymphocytes 13,49

CAFFEINE - GENERAL INFORMATION Caffeine (1,3,7-trimethylcanthine or 3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione), a well-known purine alkaloid, was described by Gennaro [8] as a white, odorless powder with a slightly bitter taste

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J Reprod Immunol 166:104326

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