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doi:10.1016/S0140-6736(23)01053-X PubMed: This trial evaluated retatrutide in 281 participants with type 2 diabetes, showing up to 16.94% weight loss and significant HbA1c reductions with favorable safety profile comparable to other GLP-1 based therapies

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We observed higher caspase-1/4/5 activity within the classical monocyte subset from COVID-19 patients when compared to HCs ( Figure 2B ), suggesting this cell subset contributes to IL-1 and IL-18 maturation during COVID-19