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J Med Ultrasound

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Research has shown that intake of bisphenol compounds is associated with the occurrence of gynecomastia in males ( EDCs disrupt hormonal equilibrium by mimicking estrogen (e.g., bisphenol A binding to ER receptors), antagonizing androgens (e.g., nonylphenol inhibiting testosterone synthesis), or interfering with the hypothalamic-pituitary-gonadal axis (e.g., atrazine inhibiting 5-reductase)

Accordingly, similar to the effects of GH on mitochondrial biogenesis, the findings above indicate the different roles of GH on autophagy during diverse physiological conditions in vivo