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Milella M, Estrov Z, Carter BZ, Harris D, Sebolt-Leopold J, Andreeff M

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Appropriate intervention against the dysregulation of these pivotal enzymes may rectify cancer metabolism and hinder tumor growth, suggesting novel therapeutic strategies

Medical management of metabolic dysfunction in PCOS

The resulting elevation in HSPA8 upregulates CD44 expression, collectively suppressing ferroptosis in HBV-associated hepatic cancer cells and thereby promoting tumor progression (Zhang et al., 2023b)