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To rule out the possibility that EMS-induced mutations in genes other than Ppa-rme-2 have resulted in the observed Tid phenotype, we generated an additional knock-out mutation by CRISPR engineering

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This has prompted WADA to evaluate possible misuses of gene editing for doping and as a consequence, has included these technologies in the definition of Gene Doping since the 2018 Prohibited List

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Verify peptide and compound integrity first