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Elucidating VSMC phenotypic transition mechanisms to bridge insights into cardiovascular disease implications

L., Lpez, L., Surez, G., Lloret, M., Rodrguez, V., Macas, D., Santana, M., Hernndez, M

Mitochondrial DNA in Innate Immune Responses and Inflammatory Pathology

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Doxy further impairs mitochondrial function, increasing ROS generation and enhancing PDT to promote more effective tumor cell destruction and stronger ICD Doxy inhibits autophagy to increase MHC-I expression on tumor cell surfaces, hence enhancing antigen presentation and cytotoxic T lymphocyte (CTL) identification, which improves tumor immunogenicity