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Overexpression of COX-2, prostaglandin E synthase-1 and prostaglandin E receptors in blood mononuclear cells and plaque of patients with carotid atherosclerosis: regulation by nuclear factor-kappaB

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The marked advanced antiangiogenic property of VGB4 compared to Peptide 18 could be due to the fact that Peptide 18 comprising VEGF-B residues led to the suppression of VEGFR1 downstream signaling, whereas VGB4 composed of VEGFR1-binding residues from VEGF-B and VEGFR2-binding residues from VEGF-A resulted in the blockade of both VEGFR1- as well as VEGFR2-mediated signaling

Telomere length A telomere is a region of repetitive nucleotide sequences at each end of a chromosome, which protect the end of the chromosome from deterioration or from fusion with neighbouring chromosomes