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I argued that [n]either Class II controls or Special Controls [could] accomplish a reasonable assurance of safety for all sectors of our general population

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10.1038/nn.2781 35 CristofaniR.CrippaV.RusminiP.CicardiM

Quantitative determination of glutamate mediated cortical neuronal injury in cell culture by lactate dehydrogenase efflux assay

[] The gut translocates nutrients, microbial products (e.g., the cell-wall components [endotoxins from Gram-negative bacteria, -glucan from fungi] and DNA, together as microbial- or pathogen-associated molecular patterns [MAMPs/PAMPs]) and metabolites (e.g., the secondary bile acids, trimethylamine [TMA]), to the liver in venous blood through the portal vein

Karlsson J-E, El-Saadi W, Ali M, Puskar W, Skogvard P, Engvall JE, et al