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Together, these G4-and nucleic acid-targeted approaches represent a paradigm shift from broad nuclear localization to molecularly precise damage, with successive advancements significantly improving PDT efficacy and reducing systemic toxicity. 6 Targeting cell membrane for enhanced PDT Due to ROS possess a short half-life and a restricted effective diffusion radius, the introduction of photosensitizers to produce ROS in situ on target organelles is essential to avoid their rapid decay

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Report of the Joint Food and Agriculture (FAO) of the United Nations/World Health Organization (WHO) Expert Consultation on Evaluation of Health and Nutritional Properties of Probiotics in Food including Powder Milk with Live Lactic Acid Bacteria Szajewska H, Setty M, Mrukowicz J, Guandalini S (2006) Probiotics in gastrointestinal diseases in children: hard and not-so-hard evidence of efficacy

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