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a commonly believed view held that the two amino peptide bonds would be hydrolyzed immediately by gastric acid, and/or the gastric and pancreatic proteases

J Biol Chem 288:1378913798

Although GSH concentrations in the vacuoles of unstressed plants have long been considered to be low or negligible [158], accumulation of GSSG in this compartment could be a physiologically important part of oxidative stress responses [176]

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This binding can induce conformational changes in -helices, which in turn regulates lipid homeostasis