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This mitochondrial failure results in the immune senescence of those same T cells and a systemic accelerated aging phenotype, marked by motor deficits, cardiovascular dysfunction, and cognitive decline (Desdn-Mic et al., 2020)

Higher concentrations of H 2 O 2 , however, impinge on both types of cascades in different ways (Fig

[PubMed] [Google Scholar] Odberg T, Jakobsen JE, Hultgren SJ, Halseide R, 2001

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