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Other studies found associations between ERCC5 mutations (rs1047768 and rs751402), PFS (progression free survival) (Sun et al., 2013) and OS (overall survival) (He et al., ERCC5 polymorphisms are involved in the efficacy of cisplatin neoadjuvant chemotherapy

This inhibition leads to critical ATP depletion, which accelerates neuronal death (65, 66)

Therefore, it remains unclear if SAM constitutes the signal or driver for Cys4p oligomerisation

The difference in the results may be due to the utilization of a noncanonical pathway of Gln metabolism in PDAC cells

Bailes, J., et al

By contrast, in the adipoctyes, the fatty acids are taken up and reassembled back into triacylglycerides (fats) and stored in fat droplets