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Gene set enrichment analysis with topGO

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The pathways activated by TrkA include Ras, Rac, PI3K, and PLC-1, which in turn activate mitogen-activated protein kinase (MAPK) cascades and Akt to generate inositol triphosphate and diacylglycerol (Sofroniew et al., 2001)

390 Furthermore, arginine depletion in a specific TME can compromise macrophage mitochondrial function, polarizing cells toward an inflammatory phenotype and demonstrating the profound impact of metabolite-driven immunomodulation

Instead, debris-like structures were observed in animals treated with high concentrations (25 or 50 M) of BPA (Fig

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