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The extent of tubulointerstitial inflammation is an independent predictor of renal survival in lupus nephritis

661 Within mitochondria, STAT3 directly interacts with and increases the activity of ND1 and SDH, enhancing OXPHOS flux

doi:10.2500/aap.2012.33.3561 14

The fact that this redox imbalance occurs as a consequence of GSH depletion may explain why several clinical trials have provided no evidence of significant cataract prevention arising from the administration of high dosages of ascorbic acid [13]