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110 Endoplasmic reticulum (ER) stress promotes neuroinflammation, activates the NF-B pathway, and contributes to cognitive decline

199,200 Elevated ATX activity in AD increases CNS LPA levels, particularly in the frontal cortex, where LPALPAR signaling activates the GiPKCMEKERKp90RSKCREB axis, increasing BACE1 and promoting A generation

10.1002/iid3.70012 80 LiH.YuanJ.DuanS.PangY

Heterochromia means that one eye, or part of one eye, has a different color

There is no crash, no jitters, and no sleep disruption from the compound itself

The researchers exposed both naturally aging mice and mice genetically modified to age more rapidly to toxic chemotherapy drugs to induce additional stress on their cells