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Microbiota modification techniques have significant potential for repairing neurotrophic deficiencies in neurodegenerative models, such as PD

For instance, interferon- (IFN-) released by cytotoxic T cells (CTLs) activates the downstream JAK-STAT1 signaling pathway, downregulating the expression of the cystine/glutamate antiporter system (xc system), thereby reducing intracellular GSH synthesis, increasing free iron levels, and ultimately inducing ferroptosis in GBM cells [91]

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The Science Behind Glutathione: Glutathione works by neutralizing free radicals, reducing oxidative stress, and promoting the regeneration of other antioxidants such as Vitamins C and E

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