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Mehmeti et al

Interestingly, copper as a catalytic cofactor in redox chemistry can modulate the activity of not only various metabolism-related enzymes e.g., COX, SOD1, ferroxidase, and LOX as mentioned above, but also some kinases

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In an observational study of 3,414 participants aged 72 to 94 years who were followed for roughly 30 years, those who actively smoked had worse results on hearing tests