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At higher levels, l-theanine blocks the release of glutamate in the brain.[ref] Related article : L-theanine research and genetic connections Magnesium: As an essential mineral, magnesium is involved in about 300 different biological pathways

Bioinformatics 37 , 24732475 (2021)

Those can include: Renal complications such as kidney stones Blood glucose dysregulation Irritability The issue of insulin resistance and glucose dysregulation is fraught with contradictions in the research, with some papers asserting that exogenous BCAAs could be a cause for insulin resistance and others claiming that genetic predisposition to diabetes and dysfunctional BCAA metabolism exist in parallel but lack a causal relationship